Research content
At the Lifescience Research Institute, while grasping the latest trends in human living organisms and health, how raw materials such as the microalga Euglena support our health and beauty as food and cosmetics, both domestically and internationally. We are working hard day and night in collaboration with our collaborative research partners. In addition, we will promote the development of new raw materials that are derived from Euglena and can deliver higher effects to the maintenance and promotion of human health.
And while continuing to pursue the potential of Euglena as a material, while aiming for the realization of lifelong health, in order to scientifically consider what humans are and what health is, and to have a deeper understanding. We will take on the challenge of realizing a world where people and the earth are healthy by conducting research on the above and utilizing it in our business.
Message from the director
Euglena aims to achieve lifelong health. When considering fundamentally reducing the gap between healthy life expectancy and average life expectancy, not only do we deal with the symptoms and disorders that have occurred as a symptomatic treatment, but we also maintain homeostasis so that the symptoms and disorders themselves do not occur. Making is important. As a result of the realization of homeostatic mental and physical development, I think that we can maximize the positive energy of human beings by facing what we want to do straight and being kind to others. Materials such as the microalgae Euglena will help to achieve this. We will continue to research to tell everyone who has picked up Euglena how it can help you instead of the Euglena Euglena And I would like to constantly think about what human health is and continue to provide innovative solutions.
Lifescience Research Institute
Director Ayaka Nakajima
Research case introduction
Effects of oral Euglena intake on stress symptoms and sleep quality
Clinical trials show that continuous intake of microalgae Euglena powder regulates autonomic balance, suppresses irritability and tension, and improves sleep quality when under work stress. confirmed.
The results of this research show the possibility of resolving the complex health anxieties of modern people such as mental and physical fatigue, stress, and lack of sleep, leading to fundamental health.
- Research content
-
ヒトの体内ではストレスから身体を防御するために自律神経系や内分泌系、免疫系のバランスをコントロールすることで身体を一定の状態に保っています。しかし、過度なストレスにより自律神経のバランスが崩れると、ストレスに対する抵抗力が弱まり、睡眠の質や意欲の低下などのさまざまな身体的・精神的症状が起こります。
今回の研究では微細藻類ユーグレナの摂取が、作業ストレス負荷をかけた際の自律神経、心理面、睡眠の質等の各種指標にどのように影響を及ぼすかを評価しました。 その結果、作業ストレス負荷がかかっている際の自律神経バランスの調整やイライラ感・緊張感の抑制、睡眠の質の改善を示すこと確認しました。Click here for the release at the time of publication of the paper
Frustration and tension under work stress, changes in sleep quality over time
Effects of paramylon on immune regulation
We confirmed the results of studies suggesting that stored polysaccharide paramylon contained in microalgae Euglena is the main component of the immunomodulatory function of Euglena. Specifically, when comparing "Euglena high content of paramilon" and "Euglena that do not accumulate paramilon" created using our original genome editing technology, we found that "it does not accumulate paramilon Euglena It was revealed that the immunomodulatory function was significantly reduced.
- Research content
-
これまでの研究を通じて、微細藻類ユーグレナの継続摂取により、主にユーグレナに含まれるパラミロンを関与成分のひとつとして、免疫バランスを保ち、インフルエンザウイルス感染症状を緩和する可能性や、関節リウマチの症状を緩和する可能性等を明らかにしてきました。また、その作用メカニズムのひとつとして、パラミロンが腸管内の免疫細胞に直接作用する可能性を発表してきました。
今回の研究では、ユーグレナ社が2019年に発表した独自の高効率ゲノム編集技術を活用して作出した「パラミロンを蓄積しないユーグレナ」が免疫系に及ぼす影響を調べることで、パラミロンの免疫系への関与のさらなる考察を行いました。 その結果、「パラミロン高含有ユーグレナ」添加では、T細胞とB細胞の活性化がみられ、免疫系への関与が確認された一方で、ゲノム編集で作出した「パラミロンを蓄積しないユーグレナ」添加ではT細胞とB細胞の活性化はみられず、免疫系への関与が確認されませんでした。Click here for the release at the time of publication of the paper
Expression of genes for T cell activation marker CD69 and B cell activation marker CD86 in mouse spleen cells
