Demonstrated wound healing effect on paramylon film
-May 2 patent application, promoting research and development for medical utilization of paramylon, a component peculiar to Euglena-

Osaka Prefecture University
Euglena Co., Ltd.

　Osaka Prefecture University (Location: Sakai City, Osaka Prefecture, President: Taketoshi Okuno) and Euglena Co., Ltd. (Headquarters: Bunkyo-ku, Tokyo, President: Mitsuru Izumo) have jointly researched "Wounds in Paramilon (Note 1) Film". Demonstrated "healing effect". The results of this research were reported at the 65th Annual Meeting of the Vitamin Society of Japan held at Hitotsubashi University (Kunitachi City, Tokyo) on Saturday, May 18th. Regarding the results of the announcement, we applied for a patent on May 2 as "a wound treatment agent containing paramylon derived from Euglena

　In recent years, wet dressing (wet treatment), which is a treatment method that keeps the wound moist with exudate, is said to promote the healing effect, and bandages and gauze made of cellulose (Note 2) are used in medical treatment for wound healing. It has been. This time, we made a film using paramylon, which has β-1,3-glucan, which is a kind of β-glucan like cellulose, and is Euglena Did.

　As a result of this study, the reduction rate of the wound area was higher when the wound was covered with paramylon film than the cellulose film used for wound healing, and the wound healing promoting effect of paramylon was confirmed. In this experiment, we used a film derived from paramylon created in cooperation with KRI Co., Ltd. (Headquarters: Kyoto City, Kyoto Prefecture, President: Hiroshi Sumitomo).
　Based on the results of this research, we plan to continue research and development in order to utilize paramylon as a wound treatment agent in the medical field.

■ The back wounds of 8-week-old male mice were coated with paramylon film, coated with cellulose film, or without film (control), and the body weight to wound area ratio were measured for 7 days.

■ The change was measured with the wound area on the 0th day of injury as 100%. There was no difference in body weight between the three groups, and the wound area was about 70% on the 7th day with the cellulose film and the control, while it healed to about 50% with the paramylon film.

<Glossary of terms>
(Note 1) Paramylon
A polysaccharide peculiar to microalgae Euglena (Japanese name: Euglena), in which glucose molecules are linearly polymerized by β-1,3-bonds. Euglena stores sugar produced by photosynthesis in the body in order to efficiently store it.
(Note 2) Cellulose
A polysaccharide that is the main component of the cell wall and fiber of plant cells, in which glucose molecules are linearly polymerized by β-1,4-bonds.

<About Euglena Co., Ltd.>
President and CEO: Mitsuru Izumo
Capital: 914.21 million yen
Head Office: 7-3-1 Hongo, Bunkyo-ku, Tokyo 7th floor, University of Tokyo Entrepreneur Plaza
Business: We develop and sell functional foods and cosmetics using microalgae Euglena (Japanese name: Euglena), and conduct research for carbon dioxide fixation and biofuel production.
* Euglena: A type of algae (Japanese name: Euglena) that grows by photosynthesis while absorbing carbon dioxide as well as being a foodstuff with 59 kinds of abundant nutrients such as vitamins, essential amino acids, and DHA. Since it is a raw material for biofuels, it is attracting attention as a material that helps solve food and environmental problems.

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-Contact for inquiries from the press-
Euglena Co., Ltd. Public Relations and IR Division