{"id":25100,"date":"2022-02-14T15:00:07","date_gmt":"2022-02-14T06:00:07","guid":{"rendered":"https:\/\/www.euglena.jp\/news\/?p=25100"},"modified":"2022-02-14T12:46:00","modified_gmt":"2022-02-14T03:46:00","slug":"20220214","status":"publish","type":"post","link":"https:\/\/www.euglena.jp\/news\/20220214\/","title":{"rendered":"\u5fae\u7d30\u85fb\u985e\u30e6\u30fc\u30b0\u30ec\u30ca\u306e\u6442\u53d6\u306b\u3088\u308a\u3001\u5fc3\u4e0d\u5168\u306e\u767a\u75c7\u306b\u3068\u3082\u306a\u3046\u8178\u5185\u74b0\u5883\u306e\u60aa\u5316\u3092\u7de9\u548c\u3057\u3001\u5fc3\u6a5f\u80fd\u4f4e\u4e0b\u3092\u6291\u3048\u308b\u3053\u3068\u3092\u793a\u5506\u3059\u308b\u7814\u7a76\u7d50\u679c\u3092\u767a\u8868\u3057\u307e\u3057\u305f"},"content":{"rendered":"

\u5fae\u7d30\u85fb\u985e\u30e6\u30fc\u30b0\u30ec\u30ca\u306e\u6442\u53d6\u306b\u3088\u308a\u3001\u5fc3\u4e0d\u5168\u306e\u767a\u75c7\u306b\u3068\u3082\u306a\u3046\u8178\u5185\u74b0\u5883\u306e\u60aa\u5316\u3092\u7de9\u548c\u3057\u3001
\n\u5fc3\u6a5f\u80fd\u4f4e\u4e0b\u3092\u6291\u3048\u308b\u3053\u3068\u3092\u793a\u5506\u3059\u308b\u7814\u7a76\u7d50\u679c\u3092\u767a\u8868\u3057\u307e\u3057\u305f<\/p>\n

\u682a\u5f0f\u4f1a\u793e\u30e6\u30fc\u30b0\u30ec\u30ca<\/p>\n

\u3000<\/strong>\u682a\u5f0f\u4f1a\u793e\u30e6\u30fc\u30b0\u30ec\u30ca\uff08\u672c\u793e\uff1a\u6771\u4eac\u90fd\u6e2f\u533a\u3001\u4ee3\u8868\u53d6\u7de0\u5f79\u793e\u9577\uff1a\u51fa\u96f2\u5145\uff09\u306f\u3001\u6771\u4eac\u5927\u5b66\u533b\u5b66\u90e8\u9644\u5c5e\u75c5\u9662\u306e\u6885\u4e95\u6b63\u5f66\u7279\u4efb\u81e8\u5e8a\u533b\u3001\u8d64\u6fa4\u5b8f\u8b1b\u5e2b\u3068\u306e\u5171\u540c\u7814\u7a76\u306b\u3088\u308a\u3001\u5fae\u7d30\u85fb\u985e\u30e6\u30fc\u30b0\u30ec\u30ca\uff08\u548c\u540d\uff1a\u30df\u30c9\u30ea\u30e0\u30b7\u3001\u4ee5\u4e0b\u300c\u30e6\u30fc\u30b0\u30ec\u30ca\u300d\uff09\u304c\u3001\u6025\u6027\u5fc3\u4e0d\u5168\u30e2\u30c7\u30eb\u30de\u30a6\u30b9\u306e\u4fbf\u79d8\u75c7\u72b6\u3092\u6539\u5584\u3057\u3001\u5fc3\u6a5f\u80fd\u3092\u6539\u5584\u3059\u308b\u3053\u3068\u3092\u793a\u3059\u7814\u7a76\u7d50\u679c\u3092\u767a\u8868\u3057\u307e\u3057\u305f\u3002\u306a\u304a\u3001\u4eca\u56de\u306e\u7814\u7a76\u6210\u679c\u306f\u3001\u300c\u7b2c84\u56de\u65e5\u672c\u5faa\u74b0\u5668\u5b66\u4f1a\u5b66\u5b66\u8853\u96c6\u4f1a\u300d\uff082020\u5e747\u670827\uff5e8\u67082\u65e5\u958b\u50ac\u203b1<\/sup>\uff09\u3067\u767a\u8868\u3001\u307e\u305f\u30012022\u5e742\u670810\u65e5\u306b\u300eCirculation Reports\u300f\u30aa\u30f3\u30e9\u30a4\u30f3\u7248\u306b\u63b2\u8f09\u3055\u308c\u307e\u3057\u305f\u3002\uff08https:\/\/www.jstage.jst.go.jp\/article\/circrep\/4\/2\/4_CR-21-0094\/_article\/-char\/ja<\/a>\uff09
\n\u203b1\u3000\u7b2c84\u56de\u65e5\u672c\u5faa\u74b0\u5668\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\u306f\u3001\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u306e\u611f\u67d3\u62e1\u5927\u3092\u8e0f\u307e\u3048\u3066\u3001\u5927\u4f1a\u306e\u73fe\u5730\u958b\u50ac\u304c\u4e2d\u6b62\u3068\u306a\u308a\u307e\u3057\u305f\u304c\u3001\u30aa\u30f3\u30e9\u30a4\u30f3\u5b66\u8853\u96c6\u4f1a\u201cThe Week for JCS 2020\u201d\u3068\u3057\u3066\u958b\u50ac\u3055\u308c\u307e\u3057\u305f<\/sup><\/p>\n

\u25a0\u7814\u7a76\u306e\u76ee\u7684
\n\u3000<\/strong>\u5fc3\u4e0d\u5168\u306f\u9ad8\u8840\u5727\u3084\u865a\u8840\u6027\u5fc3\u75be\u60a3\u3001\u5f01\u819c\u75c7\u3001\u5fc3\u7b4b\u75c7\u3001\u4e0d\u6574\u8108\u306a\u3069\u69d8\u3005\u306a\u5fc3\u75be\u60a3\u306e\u7d42\u672b\u50cf\u3067\u3001\u7f79\u60a3\u60a3\u8005\u306e\u751f\u6d3b\u306e\u8ceaQOL\uff08Quality of life\uff09\u3092\u8457\u3057\u304f\u4f4e\u4e0b\u3055\u305b\u3001\u751f\u547d\u4e88\u5f8c\u3092\u8105\u304b\u3059\u91cd\u7be4\u306a\u75be\u60a3\u3067\u3059\u3002\u8fd1\u5e74\u3001\u5fc3\u81d3\u3068\u6d88\u5316\u7ba1\u3068\u306e\u95a2\u9023\u6027\u304c\u6ce8\u76ee\u3055\u308c\u3066\u304a\u308a\u3001\u5fc3\u4e0d\u5168\u3092\u767a\u75c7\u3059\u308b\u3068\u8178\u5185\u74b0\u5883\u306b\u7570\u5e38\u3092\u304d\u305f\u3059\u3053\u3068\u304c\u660e\u3089\u304b\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u5fc3\u4e0d\u5168\u60a3\u8005\u306f\u4fbf\u79d8\u306a\u3069\u6d88\u5316\u7ba1\u75c7\u72b6\u3092\u8a34\u3048\u308b\u3053\u3068\u304c\u591a\u304f\u3001QOL\u3092\u4f4e\u4e0b\u3055\u305b\u308b\u539f\u56e0\u3068\u306a\u308a\u307e\u3059\u3002\u307e\u305f\u9006\u306b\u3001\u8178\u5185\u74b0\u5883\u306e\u7570\u5e38\u306f\u5fc3\u4e0d\u5168\u3092\u3055\u3089\u306b\u60aa\u5316\u3055\u305b\u308b\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u5f53\u793e\u3067\u306f\u3053\u308c\u307e\u3067\u306b\u3001\u30e6\u30fc\u30b0\u30ec\u30ca\u3092\u7d99\u7d9a\u7684\u306b\u6442\u53d6\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u3001\u4fbf\u79d8\u3092\u6539\u5584\u3059\u308b\u53ef\u80fd\u6027\u203b2<\/sup>\u3001\u8178\u5185\u30d5\u30ed\u30fc\u30e9\u304c\u826f\u597d\u306b\u4fdd\u305f\u308c\u308b\u53ef\u80fd\u6027\u203b3,4,5<\/sup>\u3092\u5831\u544a\u3057\u3066\u3044\u307e\u3059\u3002\u305d\u3053\u3067\u3001\u672c\u5171\u540c\u7814\u7a76\u3067\u306f\u3001\u30e6\u30fc\u30b0\u30ec\u30ca\u306e\u7d99\u7d9a\u7684\u306a\u6442\u53d6\u306b\u3088\u308a\u3001\u5fc3\u4e0d\u5168\u30e2\u30c7\u30eb\u30de\u30a6\u30b9\u306e\u5fc3\u6a5f\u80fd\u4f4e\u4e0b\u3068\u4fbf\u901a\u3092\u6539\u5584\u3059\u308b\u53ef\u80fd\u6027\u306b\u3064\u3044\u3066\u691c\u8a0e\u3057\u307e\u3057\u305f\u3002
\n\u203b2\u30002017\u5e749\u670812\u65e5\u306e\u30ea\u30ea\u30fc\u30b9\u3000https:\/\/www.euglena.jp\/news\/170912-2\/<\/a>
\n\u203b3\u30002019\u5e741\u670831\u65e5\u306e\u30ea\u30ea\u30fc\u30b9\u3000https:\/\/www.euglena.jp\/news\/20190131\/<\/a>
\n\u203b4\u30002021\u5e741\u670815\u65e5\u306e\u30ea\u30ea\u30fc\u30b9\u3000https:\/\/www.euglena.jp\/news\/20210115-2\/<\/a>
\n\u203b5\u30002021\u5e7410\u670822\u65e5\u306e\u30ea\u30ea\u30fc\u30b9\u3000https:\/\/www.euglena.jp\/news\/20211022-2\/<\/a><\/sup><\/p>\n

\u25a0\u7814\u7a76\u306e\u5185\u5bb9\u3068\u7d50\u679c
\n\u2460 \u30e6\u30fc\u30b0\u30ec\u30ca\u306e\u6442\u53d6\u306b\u3088\u308a\u3001\u5fc3\u4e0d\u5168\u30e2\u30c7\u30eb\u306e\u5fc3\u6a5f\u80fd\u4f4e\u4e0b\u304c\u6291\u5236\u3055\u308c\u307e\u3057\u305f\u3002
\n\u3000<\/strong>\u30de\u30a6\u30b9\u306b\u30e6\u30fc\u30b0\u30ec\u30ca2%\u3092\u542b\u3080\u990c\u3001\u307e\u305f\u306f\u901a\u5e38\u990c\u30928\u9031\u9593\u7d9a\u3051\u3066\u6442\u53d6\u3055\u305b\u305f\u5f8c\u3001\u30a4\u30bd\u30d7\u30ed\u30c6\u30ec\u30ce\u30fc\u30eb\uff08ISO\u4ee5\u4e0b\u3001\u300cISO\u300d\uff09\u203b6<\/sup>\u30927\u65e5\u9593\u6295\u4e0e\u3057\u305f\u5fc3\u4e0d\u5168\u30e2\u30c7\u30eb\u30de\u30a6\u30b9\u3092\u4f5c\u6210\u3057\u307e\u3057\u305f\u3002\u901a\u5e38\u990c\u3092\u6442\u53d6\u3057\u305fISO\u6295\u4e0e\u7fa4\u3067\u306f\u3001\u751f\u7406\u98df\u5869\u6c34\uff08\u4ee5\u4e0b\u3001\u300c\u751f\u98df\u300d\uff09\u3092\u6295\u4e0e\u3057\u305f\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u7fa4\u3068\u6bd4\u3079\u3066\u3001\u5fc3\u5ba4\u58c1\u306e\u80a5\u539a\u203b7<\/sup>\u3084\u5fc3\u53ce\u7e2e\u80fd\u203b8<\/sup>\u306e\u4f4e\u4e0b\u306a\u3069\u304c\u8a8d\u3081\u3089\u308c\u307e\u3057\u305f\uff08\u56f31\uff09\u3002\u4e00\u65b9\u3067\u30e6\u30fc\u30b0\u30ec\u30ca\u3092\u6442\u53d6\u3057\u305fISO\u6295\u4e0e\u7fa4\u3067\u306f\u3001\u58c1\u80a5\u539a\u306b\u5f71\u97ff\u306f\u898b\u3089\u308c\u306a\u3044\u3082\u306e\u306e\u3001\u5fc3\u53ce\u7e2e\u80fd\u306e\u4f4e\u4e0b\u304c\u6291\u5236\u3055\u308c\u307e\u3057\u305f\u3002\u307e\u305f\u5fc3\u4e0d\u5168\u306e\u969b\u306b\u4e0a\u6607\u3059\u308b\u5fc3\u623f\u6027\u30ca\u30c8\u30ea\u30a6\u30e0\u5229\u5c3f\u30da\u30d7\u30c1\u30c9\uff08ANP\uff09\u203b9<\/sup>\u306e\u907a\u4f1d\u5b50\u767a\u73fe\u91cf\u304c\u30e6\u30fc\u30b0\u30ec\u30ca\u6442\u53d6\u306b\u3088\u3063\u3066\u4e0a\u6607\u304c\u6291\u5236\u3055\u308c\u3066\u3044\u308b\u7d50\u679c\u3082\u3042\u308f\u305b\u3066\u5f97\u3089\u308c\u307e\u3057\u305f\uff08\u56f3\uff12\uff09\u3002
\n\u203b6\u3000ISO\u306f\u3001\u5fc3\u81d3\u306e\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3\u53d7\u5bb9\u4f53\u306b\u5f37\u304f\u4f5c\u7528\u3059\u308b\u85ac\u5264\u3067\u3042\u308a\u3001\u5fc3\u4e0d\u5168\u30e2\u30c7\u30eb\u306e\u4f5c\u6210\u306b\u5e83\u304f\u4f7f\u7528\u3055\u308c\u307e\u3059\u3002\u672c\u7814\u7a76\u3067\u306f\u751f\u98df\u306b\u6eb6\u89e3\u3057\u3066\u6295\u4e0e\u3057\u307e\u3057\u305f\u3002ISO\u3092\u6eb6\u89e3\u3057\u3066\u3044\u306a\u3044\u751f\u98df\u3092\u6295\u4e0e\u3057\u305f\u30e2\u30c7\u30eb\u3092\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3068\u3057\u3066\u3044\u307e\u3059
\n\u203b7\u3000\u5fc3\u81d3\u306b\u8ca0\u62c5\u304c\u304b\u304b\u308b\u3068\u3001\u5fc3\u81d3\u306e\u7b4b\u8089\u306e\u58c1\u304c\u80a5\u539a\u3057\u3001\u5206\u539a\u304f\u306a\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059
\n\u203b8\u3000\u5fc3\u53ce\u7e2e\u529b\u306f\u3001\u5fc3\u81d3\u304c\u62e1\u5f35\u3057\u305f\u3068\u304d\u306e\u5927\u304d\u3055\u304b\u3089\u3001\u4f55%\u53ce\u7e2e\u3057\u305f\u304b\u3092\u793a\u3057\u307e\u3059
\n\u203b9\u3000\u5fc3\u623f\u6027\u30ca\u30c8\u30ea\u30a6\u30e0\u5229\u5c3f\u30da\u30d7\u30c1\u30c9\uff08ANP\uff09\u306f\u3001\u5fc3\u81d3\u3067\u5408\u6210\u30fb\u8caf\u8535\u3055\u308c\u3001\u8840\u6db2\u4e2d\u306b\u5206\u6ccc\u3055\u308c\u308b\u30db\u30eb\u30e2\u30f3\u3067\u3059<\/sup><\/p>\n

<\/p>\n

\u56f31\uff1a\u30e6\u30fc\u30b0\u30ec\u30ca\u306b\u3088\u308b\u5fc3\u4e0d\u5168\u30e2\u30c7\u30eb\u30de\u30a6\u30b9\u306e\u5fc3\u6a5f\u80fd\u4f4e\u4e0b\u306b\u5bfe\u3059\u308b\u5f71\u97ff
\n\u30e6\u30fc\u30b0\u30ec\u30ca(\uff0d),ISO(\uff0d)\uff1a\u901a\u5e38\u990c\u3092\u4e0e\u3048\u305f\u3042\u3068\u3001\u751f\u98df\u3092\u6295\u4e0e\u3057\u305f\u30de\u30a6\u30b9\u3001n=13
\n\u30e6\u30fc\u30b0\u30ec\u30ca(\uff0b),ISO(\uff0d)\uff1a\u30e6\u30fc\u30b0\u30ec\u30ca\u3092\u4e0e\u3048\u305f\u3042\u3068\u3001\u751f\u98df\u3092\u6295\u4e0e\u3057\u305f\u30de\u30a6\u30b9\u3001n=12
\n\u30e6\u30fc\u30b0\u30ec\u30ca(\uff0d),ISO(\uff0b)\uff1a\u901a\u5e38\u990c\u3092\u4e0e\u3048\u305f\u3042\u3068\u3001ISO\u3092\u6295\u4e0e\u3057\u305f\u30de\u30a6\u30b9\u3001n=12
\n\u30e6\u30fc\u30b0\u30ec\u30ca(\uff0b),ISO(\uff0b\uff09\uff1a\u30e6\u30fc\u30b0\u30ec\u30ca\u3092\u4e0e\u3048\u305f\u3042\u3068\u3001ISO\u3092\u6295\u4e0e\u3057\u305f\u30de\u30a6\u30b9\u3001n=13
\n* P<0.05, ** P<0.01, \u4e00\u5143\u914d\u7f6e\u5206\u6563\u5206\u6790\u3001\u591a\u91cd\u6bd4\u8f03\u691c\u5b9a\uff08\u30dc\u30f3\u30d5\u30a7\u30ed\u30fc\u30cb\u6cd5\uff09
\n\u30dc\u30c3\u30af\u30b9\u5185\u306e\u6a2a\u7dda\u306f\u3001\u4e2d\u592e\u5024\u3092\u793a\u3057\u307e\u3059\u3002\u4e0a\u4e0b\u7aef\u306e\u6a2a\u7dda\u306f\u6700\u5927\u5024\u3068\u6700\u5c0f\u5024\u3092\u3001\u30dc\u30c3\u30af\u30b9\u306f\u30c7\u30fc\u30bf\u306e\u5206\u5e03\u3092\u793a\u3057\u307e\u3059\uff08\u7b2c\u4e00\u56db\u5206\u4f4d\u6570\u3001\u7b2c\u4e09\u56db\u5206\u4f4d\u6570\uff09\u3002<\/sup><\/p>\n

<\/p>\n

\u56f32\uff1a\u30e6\u30fc\u30b0\u30ec\u30ca\u306b\u3088\u308b\u5fc3\u623f\u6027\u30ca\u30c8\u30ea\u30a6\u30e0\u5229\u5c3f\u30da\u30d7\u30c1\u30c9\uff08ANP\uff09\u306e\u907a\u4f1d\u5b50\u767a\u73fe\u306b\u5bfe\u3059\u308b\u5f71\u97ff
\n\u30e6\u30fc\u30b0\u30ec\u30ca(\uff0d),ISO(\uff0d)\uff1a\u901a\u5e38\u990c\u3092\u4e0e\u3048\u305f\u3042\u3068\u3001\u751f\u98df\u3092\u6295\u4e0e\u3057\u305f\u30de\u30a6\u30b9\u3001n=9
\n\u30e6\u30fc\u30b0\u30ec\u30ca(\uff0b),ISO(\uff0d)\uff1a\u30e6\u30fc\u30b0\u30ec\u30ca\u3092\u4e0e\u3048\u305f\u3042\u3068\u3001\u751f\u98df\u3092\u6295\u4e0e\u3057\u305f\u30de\u30a6\u30b9\u3001n=9
\n\u30e6\u30fc\u30b0\u30ec\u30ca(\uff0d),ISO(\uff0b)\uff1a\u901a\u5e38\u990c\u3092\u4e0e\u3048\u305f\u3042\u3068\u3001ISO\u3092\u6295\u4e0e\u3057\u305f\u30de\u30a6\u30b9\u3001n=9
\n\u30e6\u30fc\u30b0\u30ec\u30ca(\uff0b),ISO(\uff0b\uff09\uff1a\u30e6\u30fc\u30b0\u30ec\u30ca\u3092\u4e0e\u3048\u305f\u3042\u3068\u3001ISO\u3092\u6295\u4e0e\u3057\u305f\u30de\u30a6\u30b9\u3001n=8
\n* P<0.05, ** P<0.01, \u4e00\u5143\u914d\u7f6e\u5206\u6563\u5206\u6790\u3001\u591a\u91cd\u6bd4\u8f03\u691c\u5b9a\uff08\u30dc\u30f3\u30d5\u30a7\u30ed\u30fc\u30cb\u6cd5\uff09
\n\u5fc3\u81d3\u7d44\u7e54\u304b\u3089\u30e1\u30c3\u30bb\u30f3\u30b8\u30e3\u30fcRNA\uff08mRNA\uff09\u3092\u62bd\u51fa\u3057\u3001\u5b9a\u91cf\u7684PCR\u3092\u7528\u3044\u3066ANP\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u91cf\u3092\u6e2c\u5b9a\u3057\u307e\u3057\u305f\u3002
\n\u767a\u73fe\u91cf\u304c\u5909\u52d5\u305b\u305a\u5b89\u5b9a\u3057\u3066\u3044\u308bGapdh\u907a\u4f1d\u5b50\u3092\u7528\u3044\u3066\u3001\u5404\u30b5\u30f3\u30d7\u30eb\u306b\u3064\u3044\u3066\u30b5\u30f3\u30d7\u30eb\u91cf\u3092\u88dc\u6b63\u3057\u307e\u3057\u305f\u3002
\n\u30dc\u30c3\u30af\u30b9\u5185\u306e\u6a2a\u7dda\u306f\u3001\u4e2d\u592e\u5024\u3092\u793a\u3057\u307e\u3059\u3002\u4e0a\u4e0b\u7aef\u306e\u6a2a\u7dda\u306f\u6700\u5927\u5024\u3068\u6700\u5c0f\u5024\u3092\u3001\u30dc\u30c3\u30af\u30b9\u306f\u30c7\u30fc\u30bf\u306e\u5206\u5e03\u3092\u793a\u3057\u307e\u3059\uff08\u7b2c\u4e00\u56db\u5206\u4f4d\u6570\u3001\u7b2c\u4e09\u56db\u5206\u4f4d\u6570\uff09\u3002<\/sup><\/p>\n

\u2461 \u30e6\u30fc\u30b0\u30ec\u30ca\u306e\u6442\u53d6\u306b\u3088\u308a\u3001\u5fc3\u4e0d\u5168\u30e2\u30c7\u30eb\u30de\u30a6\u30b9\u306e\u4fbf\u79d8\u75c7\u72b6\u304c\u6539\u5584\u3057\u307e\u3057\u305f\u3002
\n\u3000<\/strong>\u5fc3\u4e0d\u5168\u30e2\u30c7\u30eb\u30de\u30a6\u30b9\u306e\u6d88\u5316\u7ba1\u6a5f\u80fd\u30fb\u4fbf\u79d8\u75c7\u72b6\u306b\u3064\u3044\u3066\u8abf\u3079\u308b\u305f\u3081\u3001\u7d76\u98df\u5f8c\u306e\u30de\u30a6\u30b9\u306e\u76f2\u8178\u5185\u306b\u6b8b\u5b58\u3059\u308b\u7cde\u4fbf\u91cf\u3092\u8a55\u4fa1\u3057\u305f\u3068\u3053\u308d\u3001\u751f\u98df\u3092\u6295\u4e0e\u3057\u305f\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u7fa4\u3068\u6bd4\u3079\u3066\u3001\u901a\u5e38\u990c\u3092\u6442\u53d6\u3057\u305fISO\u6295\u4e0e\u7fa4\u306b\u304a\u3044\u3066\u76f2\u8178\u91cd\u91cf\u304c\u6709\u610f\u306b\u5897\u52a0\u3057\u3066\u3044\u307e\u3057\u305f\u3002\u30e6\u30fc\u30b0\u30ec\u30ca\u3092\u6442\u53d6\u3057\u305fISO\u6295\u4e0e\u7fa4\u3067\u306f\u3001\u901a\u5e38\u990c\u3092\u6442\u53d6\u3057\u305fISO\u6295\u4e0e\u7fa4\u3068\u6bd4\u3079\u3066\u3001\u76f2\u8178\u5185\u5bb9\u7269\u306f\u6e1b\u5c11\u3057\u305f\u3053\u3068\u304b\u3089\u3001\u4fbf\u79d8\u75c7\u72b6\u304c\u6539\u5584\u3057\u305f\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u307e\u3057\u305f\uff08\u56f33\uff09\u3002\u307e\u305f\u3001\u901a\u5e38\u990c\u3092\u6442\u53d6\u3057\u305fISO\u6295\u4e0e\u7fa4\u306b\u304a\u3044\u3066\u3001\u6d88\u5316\u7ba1\u306e\u8815\u52d5\u904b\u52d5\u80fd\u203b10<\/sup>\u304c\u6709\u610f\u306b\u4f4e\u4e0b\u3057\u3066\u3044\u307e\u3057\u305f\u304c\u3001\u30e6\u30fc\u30b0\u30ec\u30ca\u3092\u6442\u53d6\u3057\u305fISO\u6295\u4e0e\u7fa4\u3067\u306f\u3001\u8815\u52d5\u904b\u52d5\u80fd\u306e\u56de\u5fa9\u304c\u8a8d\u3081\u3089\u308c\u307e\u3057\u305f\uff08\u56f34\uff09\u3002\u4e00\u65b9\u3067\u3001\u5927\u8178\u5185\u306b\u6b8b\u5b58\u3059\u308b\u7cde\u4fbf\u500b\u4f53\u6570\u306e\u6bd4\u8f03\u3084\u7cde\u4fbf\u4e2d\u306b\u542b\u307e\u308c\u308b\u6c34\u5206\u91cf\u306e\u6bd4\u8f03\u3092\u884c\u3044\u307e\u3057\u305f\u304c\u3001\u3053\u308c\u3089\u306b\uff14\u7fa4\u9593\u3067\u5927\u304d\u306a\u9055\u3044\u306f\u3042\u308a\u307e\u305b\u3093\u3067\u3057\u305f\uff08\u56f3\uff15\uff09\u3002\u3053\u308c\u3089\u306e\u7d50\u679c\u304b\u3089\u3001\u30e6\u30fc\u30b0\u30ec\u30ca\u6442\u53d6\u306b\u3088\u308a\u6d88\u5316\u7ba1\u306e\u8815\u52d5\u904b\u52d5\u304c\u4fc3\u9032\u3055\u308c\u308b\u3053\u3068\u3067\u3001\u5fc3\u4e0d\u5168\u306b\u304a\u3051\u308b\u4fbf\u79d8\u75c7\u72b6\u304c\u6539\u5584\u3059\u308b\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u307e\u3057\u305f\u3002
\n\u3000<\/strong>\u307e\u305f\u5c0f\u8178\u30fb\u5927\u8178\u306e\u7d44\u7e54\u50cf\u306b\u3064\u3044\u3066\u691c\u8a3c\u3092\u884c\u3063\u305f\u3068\u3053\u308d\u3001\u901a\u5e38\u990c\u3092\u6442\u53d6\u3057\u305fISO\u6295\u4e0e\u7fa4\u3067\u306f\u5c0f\u8178\u304a\u3088\u3073\u5927\u8178\u306e\u7d68\u6bdb\u203b11<\/sup>\u304c\u6709\u610f\u306b\u77ed\u7e2e\u3057\u3066\u3044\u305f\u3082\u306e\u304c\u3001\u30e6\u30fc\u30b0\u30ec\u30ca\u3092\u6442\u53d6\u3057\u305fISO\u6295\u4e0e\u7fa4\u3067\u306f\u7d68\u6bdb\u306e\u77ed\u7e2e\u304c\u6291\u5236\u3055\u308c\u3066\u3044\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u3068\u306a\u308a\u3001\u8178\u5185\u74b0\u5883\u306e\u6539\u5584\u304c\u793a\u5506\u3055\u308c\u307e\u3057\u305f\uff08\u56f36\uff09\u3002
\n\u203b10\u3000\u6d88\u5316\u3057\u305f\u98df\u3079\u7269\u3092\u3001\u8178\u304c\u4f38\u3073\u7e2e\u307f\u3092\u304f\u308a\u8fd4\u3057\u3066\u8178\u5185\u3092\u79fb\u52d5\u3055\u305b\u3001\u4f53\u5916\u3078\u6392\u51fa\u3059\u308b\u52d5\u304d\u3067\u3059<\/sup>
\n\u203b11\u3000\u8178\u5185\u74b0\u5883\u304c\u60aa\u5316\u3059\u308b\u3068\u8178\u4e0a\u76ae\u306e\u7d68\u6bdb\u304c\u77ed\u304f\u306a\u308a\u3001\u6804\u990a\u6442\u53d6\u4e0d\u826f\u3001\u4fbf\u901a\u306e\u60aa\u5316\u3084\u514d\u75ab\u7cfb\u306e\u4f4e\u4e0b\u306b\u3064\u306a\u304c\u308a\u3084\u3059\u3044\u3068\u8a00\u308f\u308c\u3066\u3044\u307e\u3059<\/sup><\/p>\n

<\/p>\n

\u56f33\uff1a\u30e6\u30fc\u30b0\u30ec\u30ca\u306b\u3088\u308b\u5fc3\u4e0d\u5168\u30e2\u30c7\u30eb\u30de\u30a6\u30b9\u306e\u4fbf\u79d8\u75c7\u72b6\u306b\u5bfe\u3059\u308b\u5f71\u97ff
\n\u30e6\u30fc\u30b0\u30ec\u30ca(\uff0d),ISO(\uff0d)\uff1a\u901a\u5e38\u990c\u3092\u4e0e\u3048\u305f\u3042\u3068\u3001\u751f\u98df\u3092\u6295\u4e0e\u3057\u305f\u30de\u30a6\u30b9\u3001n=9
\n\u30e6\u30fc\u30b0\u30ec\u30ca(\uff0b),ISO(\uff0d)\uff1a\u30e6\u30fc\u30b0\u30ec\u30ca\u3092\u4e0e\u3048\u305f\u3042\u3068\u3001\u751f\u98df\u3092\u6295\u4e0e\u3057\u305f\u30de\u30a6\u30b9\u3001n=9
\n\u30e6\u30fc\u30b0\u30ec\u30ca(\uff0d),ISO(\uff0b)\uff1a\u901a\u5e38\u990c\u3092\u4e0e\u3048\u305f\u3042\u3068\u3001ISO\u3092\u6295\u4e0e\u3057\u305f\u30de\u30a6\u30b9\u3001n=9
\n\u30e6\u30fc\u30b0\u30ec\u30ca(\uff0b),ISO(\uff0b\uff09\uff1a\u30e6\u30fc\u30b0\u30ec\u30ca\u3092\u4e0e\u3048\u305f\u3042\u3068\u3001ISO\u3092\u6295\u4e0e\u3057\u305f\u30de\u30a6\u30b9\u3001n=8
\n* P<0.05, ** P<0.01, \u4e00\u5143\u914d\u7f6e\u5206\u6563\u5206\u6790\u3001\u591a\u91cd\u6bd4\u8f03\u691c\u5b9a\uff08\u30dc\u30f3\u30d5\u30a7\u30ed\u30fc\u30cb\u6cd5\uff09
\n\u30dc\u30c3\u30af\u30b9\u5185\u306e\u6a2a\u7dda\u306f\u3001\u4e2d\u592e\u5024\u3092\u793a\u3057\u307e\u3059\u3002\u4e0a\u4e0b\u7aef\u306e\u6a2a\u7dda\u306f\u6700\u5927\u5024\u3068\u6700\u5c0f\u5024\u3092\u3001\u30dc\u30c3\u30af\u30b9\u306f\u30c7\u30fc\u30bf\u306e\u5206\u5e03\u3092\u793a\u3057\u307e\u3059\uff08\u7b2c\u4e00\u56db\u5206\u4f4d\u6570\u3001\u7b2c\u4e09\u56db\u5206\u4f4d\u6570\uff09\u3002<\/sup><\/p>\n

<\/p>\n

\u56f34\uff1a\u30e6\u30fc\u30b0\u30ec\u30ca\u306b\u3088\u308b\u5fc3\u4e0d\u5168\u30e2\u30c7\u30eb\u306e\u6d88\u5316\u7ba1\u8815\u52d5\u904b\u52d5\u306e\u4f4e\u4e0b\u306b\u5bfe\u3059\u308b\u5f71\u97ff
\n\u6d88\u5316\u7ba1\u75c7\u72b6\u3092\u8abf\u3079\u308b\u305f\u3081\u3001\u30de\u30a6\u30b9\u306b\u8272\u7d20\u30c8\u30ea\u30d1\u30f3\u30d6\u30eb\u30fc\u3092\u6442\u990c\u3055\u305b\u305f\u3042\u3068\u3001\u4e00\u5b9a\u6642\u9593\u5185\u306b\u6d88\u5316\u7ba1\u5185\u3092\u8272\u7d20\u304c\u9032\u3093\u3060\u8ddd\u96e2\uff08\u30c8\u30ea\u30d1\u30f3\u30d6\u30eb\u30fc\u5230\u9054\u8ddd\u96e2\uff09\u3092\u8a08\u6e2c\u3059\u308b\u3053\u3068\u3067\u8815\u52d5\u904b\u52d5\u80fd\u3092\u6e2c\u5b9a\u3057\u307e\u3057\u305f\u3002\u5c0f\u8178\u5168\u9577\u306b\u5bfe\u3059\u308b\u30c8\u30ea\u30d1\u30f3\u30d6\u30eb\u30fc\u5230\u9054\u8ddd\u96e2\u304c\u9577\u3044\u307b\u3069\u3001\u6d88\u5316\u7ba1\u8815\u52d5\u904b\u80fd\u304c\u9ad8\u3044\u3053\u3068\u3092\u793a\u3057\u307e\u3059\u3002
\n\u30e6\u30fc\u30b0\u30ec\u30ca(\uff0d),ISO(\uff0d)\uff1a\u901a\u5e38\u990c\u3092\u4e0e\u3048\u305f\u3042\u3068\u3001\u751f\u98df\u3092\u6295\u4e0e\u3057\u305f\u30de\u30a6\u30b9\u3001n=7
\n\u30e6\u30fc\u30b0\u30ec\u30ca(\uff0b),ISO(\uff0d)\uff1a\u30e6\u30fc\u30b0\u30ec\u30ca\u3092\u4e0e\u3048\u305f\u3042\u3068\u3001\u751f\u98df\u3092\u6295\u4e0e\u3057\u305f\u30de\u30a6\u30b9\u3001n=6
\n\u30e6\u30fc\u30b0\u30ec\u30ca(\uff0d),ISO(\uff0b)\uff1a\u901a\u5e38\u990c\u3092\u4e0e\u3048\u305f\u3042\u3068\u3001ISO\u3092\u6295\u4e0e\u3057\u305f\u30de\u30a6\u30b9\u3001n=7
\n\u30e6\u30fc\u30b0\u30ec\u30ca(\uff0b),ISO(\uff0b\uff09\uff1a\u30e6\u30fc\u30b0\u30ec\u30ca\u3092\u4e0e\u3048\u305f\u3042\u3068\u3001ISO\u3092\u6295\u4e0e\u3057\u305f\u30de\u30a6\u30b9\u3001n=7
\n* P<0.05, \u4e00\u5143\u914d\u7f6e\u5206\u6563\u5206\u6790\u3001\u591a\u91cd\u6bd4\u8f03\u691c\u5b9a\uff08\u30dc\u30f3\u30d5\u30a7\u30ed\u30fc\u30cb\u6cd5\uff09
\n\u30dc\u30c3\u30af\u30b9\u5185\u306e\u6a2a\u7dda\u306f\u3001\u4e2d\u592e\u5024\u3092\u793a\u3057\u307e\u3059\u3002\u4e0a\u4e0b\u7aef\u306e\u6a2a\u7dda\u306f\u6700\u5927\u5024\u3068\u6700\u5c0f\u5024\u3092\u3001\u30dc\u30c3\u30af\u30b9\u306f\u30c7\u30fc\u30bf\u306e\u5206\u5e03\u3092\u793a\u3057\u307e\u3059\uff08\u7b2c\u4e00\u56db\u5206\u4f4d\u6570\u3001\u7b2c\u4e09\u56db\u5206\u4f4d\u6570\uff09\u3002<\/sup><\/p>\n

 <\/p>\n

<\/p>\n

\u56f35\uff1a\u5fc3\u4e0d\u5168\u30e2\u30c7\u30eb\u306b\u304a\u3051\u308b\u5927\u8178\u5185\u7cde\u4fbf\u6570\u3084\u7cde\u4fbf\u4e2d\u306e\u6c34\u5206\u5272\u5408\u306e\u5909\u5316
\n\u30e6\u30fc\u30b0\u30ec\u30ca(\uff0d),ISO(\uff0d)\uff1a\u901a\u5e38\u990c\u3092\u4e0e\u3048\u305f\u3042\u3068\u3001\u751f\u98df\u3092\u6295\u4e0e\u3057\u305f\u30de\u30a6\u30b9\u3001n=9
\n\u30e6\u30fc\u30b0\u30ec\u30ca(\uff0b),ISO(\uff0d)\uff1a\u30e6\u30fc\u30b0\u30ec\u30ca\u3092\u4e0e\u3048\u305f\u3042\u3068\u3001\u751f\u98df\u3092\u6295\u4e0e\u3057\u305f\u30de\u30a6\u30b9\u3001n=9
\n\u30e6\u30fc\u30b0\u30ec\u30ca(\uff0d),ISO(\uff0b)\uff1a\u901a\u5e38\u990c\u3092\u4e0e\u3048\u305f\u3042\u3068\u3001ISO\u3092\u6295\u4e0e\u3057\u305f\u30de\u30a6\u30b9\u3001n=9
\n\u30e6\u30fc\u30b0\u30ec\u30ca(\uff0b),ISO(\uff0b\uff09\uff1a\u30e6\u30fc\u30b0\u30ec\u30ca\u3092\u4e0e\u3048\u305f\u3042\u3068\u3001ISO\u3092\u6295\u4e0e\u3057\u305f\u30de\u30a6\u30b9\u3001n=8
\n\u6709\u610f\u5dee\u306a\u3057, \u4e00\u5143\u914d\u7f6e\u5206\u6563\u5206\u6790\u3001\u591a\u91cd\u6bd4\u8f03\u691c\u5b9a\uff08\u30dc\u30f3\u30d5\u30a7\u30ed\u30fc\u30cb\u6cd5\uff09
\n\u30dc\u30c3\u30af\u30b9\u5185\u306e\u6a2a\u7dda\u306f\u3001\u4e2d\u592e\u5024\u3092\u793a\u3057\u307e\u3059\u3002\u4e0a\u4e0b\u7aef\u306e\u7dda\u6a2a\u306f\u6700\u5927\u5024\u3068\u6700\u5c0f\u5024\u3092\u3001\u30dc\u30c3\u30af\u30b9\u306f\u30c7\u30fc\u30bf\u306e\u5206\u5e03\u3092\u793a\u3057\u307e\u3059\uff08\u7b2c\u4e00\u56db\u5206\u4f4d\u6570\u3001\u7b2c\u4e09\u56db\u5206\u4f4d\u6570\uff09\u3002<\/sup><\/p>\n

<\/p>\n

\u56f3\uff16\uff1a\u30e6\u30fc\u30b0\u30ec\u30ca\u306b\u3088\u308b\u5fc3\u4e0d\u5168\u30e2\u30c7\u30eb\u306e\u5c0f\u8178\u304a\u3088\u3073\u5927\u8178\u306e\u7d68\u6bdb\u306b\u5bfe\u3059\u308b\u5f71\u97ff
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\n\u30e6\u30fc\u30b0\u30ec\u30ca(\uff0b),ISO(\uff0d)\uff1a\u30e6\u30fc\u30b0\u30ec\u30ca\u3092\u4e0e\u3048\u305f\u3042\u3068\u3001\u751f\u98df\u3092\u6295\u4e0e\u3057\u305f\u30de\u30a6\u30b9\u3001n=9
\n\u30e6\u30fc\u30b0\u30ec\u30ca(\uff0d),ISO(\uff0b)\uff1a\u901a\u5e38\u990c\u3092\u4e0e\u3048\u305f\u3042\u3068\u3001ISO\u3092\u6295\u4e0e\u3057\u305f\u30de\u30a6\u30b9\u3001n=9
\n\u30e6\u30fc\u30b0\u30ec\u30ca(\uff0b\uff09,ISO(\uff0b\uff09\uff1a\u30e6\u30fc\u30b0\u30ec\u30ca\u3092\u4e0e\u3048\u305f\u3042\u3068\u3001ISO\u3092\u6295\u4e0e\u3057\u305f\u30de\u30a6\u30b9\u3001n=8
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\n* P<0.05, ** P<0.01, \u4e00\u5143\u914d\u7f6e\u5206\u6563\u5206\u6790\u3001\u591a\u91cd\u6bd4\u8f03\u691c\u5b9a\uff08\u30dc\u30f3\u30d5\u30a7\u30ed\u30fc\u30cb\u6cd5\uff09
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